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Peña Plastic Surgery

Board-Certified Plastic Surgeon

239-348-7362
  • About Us
    • Medical Director
      • About Manuel Peña, M.D.
      • Practice Philosophy
      • Choosing a Cosmetic Surgeon
      • Comparing Providers
      • Questions to Ask Your Cosmetic Surgeon
      • Am I a Good Candidate for Cosmetic Surgery?
    • Our Practice
      • Facility
      • Meet the Staff
      • Consultation (Office & Virtual)
      • Computer Imaging (Vectra 3D)
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    • Media
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  • Results
    • Face & Injectables
      • Facelift
      • Rhinoplasty
      • Lip Augmentation
      • Dermal Fillers / Injectables
    • Breast Procedures
      • Breast Augmentation
      • Breast Lift
      • Breast Reduction
    • Body Contouring Procedures
      • Arm Lift
      • Body Contouring
      • Liposuction
      • Mommy Makeover
      • Tummy Tuck
    • Laser & RF Energy Procedures
      • Laser Rejuvenation Gallery
      • Sofwave™ Gallery
      • ThermiTight™ Gallery
      • ThermiVa™ Gallery
  • Surgical
    • Face Enhancements
      • Brow Lift
      • Eyelid Lift (Blepharoplasty)
      • Facelift (Mini or S-lift)
      • Facelift (Full)
      • Facial Fat Grafting
      • Facial Implants
      • Lip Augmentation
      • Nose Shaping (Rhinoplasty)
      • Neck Lift & Thread Lift
      • Otoplasty (Ear Pinning)
      • Gauging & Earlobe Repair
    • Body Contouring
      • Abdominoplasty (Tummy Tuck)
      • Arm Lift (Brachioplasty)
      • Body Lift
      • Fat Grafting
      • Liposuction
      • Mommy Makeover
      • Post-Bariatric Body Contouring
    • Breast Enhancements
      • Breast Augmentation
      • Breast Lift
      • Breast Implant Removal, Lift & Fat Grafts
      • Breast Asymmetry
      • Female Breast Reduction
      • Male Breast Reduction
  • Non-surgical
    • Injectables
      • BOTOX® Cosmetic
      • DAXXIFY®
      • Dysport®
      • Microneedling (Innopen™)
      • Microneedling (PRP)
      • Juvéderm® Ultra XC / Ultra Plus XC
      • Juvéderm® Volbella™ XC
      • Juvéderm® Vollure XC
      • Juvéderm® Voluma™ XC
      • Lip Augmentation
      • PRO-NOX™
      • PRP Facial & Fat Replacement
      • Radiesse®
      • Restylane-L®
      • Restylane® Defyne, Lyft Refyne & Silk
      • Restylane® Kysse
      • Sculptra® Aesthetic
      • Teoxane Fillers (RHA2, RHA3, RHA4)
    • Body Contouring & Rejuvenation
      • “Instant” Neck Lift
      • Skin Tightening (ThermiTight®)
      • SculpSure® Fat Reduction
      • Fractional Skin Resurfacing & Tightening (Morpheus8)
    • Specialized Services
      • Hair Restoration (Microneedling with PRP)
      • Vein Treatment Sclerotherapy
      • Vaginal Rejuvenaton (THERMIva)
    • Skin Care
      • HydraFacial MD®
      • Latisse® Eyelash Enhancement
      • La Piel Full-Service Medical Spa
      • Sofwave™
  • Laser RF Light Technology
    • Lasers & Radio Frequency (RF)
      • Fractional CO2 (SmartXide Dot™)
      • FaceTite Skin Tightening
      • Injectable & RF Skin Tightening (Accutite)
      • Laser Hair Removal
      • Facial Rejuvenation (ThermiSmooth®)
    • Light Sources
      • Intense Pulsed Light (IPL)
      • Lumecca IPL
  • Reviews
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Announcing A New Patient Comfort System That You Can Control

PRO-NOX™

PRO-NOX™ Naples, FLDr. Manuel Peña is always concerned with the comfort of his patients at his Naples, Florida practice, Peña Plastic Surgery. Dr. Peña is pleased that he can now provide his patients with the PRO-NOX™ Nitrous Oxide System which provides patients with relief from any associated pain and anxiety that may coincide with a cosmetic procedure.

What is PRO-NOX™?

PRO-NOX™ is a 50/50 combination of oxygen (O2) and nitrous oxide (N2O). This safe mixture of 50% Nitrous Oxide and 50% Oxygen allows patients to self-administer the vapor blend via a face mask. This means you are in control of the strength of the dose by breathing as you need relief.

The benefit of using PRO-NOX™

PRO-NOX™ Naples, FLThe relief is almost immediate, you will be alert for your procedure, and shortly after your treatment ends the nitrous oxide effect will clear from your system.* You will be able to drive yourself to and from your appointment if the doctor agrees. Certain surgical procedures may preclude you from driving. The biggest benefits of PRO-NOX™ are that it is effective, non-addictive, and affordable.

Which procedures can you use PRO-NOX™ for?

PRO-NOX™ can be used for any cosmetic procedure that allows you to remain awake, such as injectable treatments, PRP treatments, and Laser/ RF/ Light treatments.

Who is a candidate for PRO-NOX™?

Patients who are nervous about pain or have heightened levels of anxiety when dealing with medical treatments may be a candidate for PRO-NOX™. During your consultation, your medical history will be reviewed to see if there are any contraindications which may prevent you from using PRO-NOX™ System.

Schedule your consultation

If you are searching for an expert in his field to assist you in either improving your look or rejuvenating your appearance to a more youthful you, contact Dr. Manuel Peña at Peña Plastic Surgery. He is a board-certified plastic surgeon who genuinely cares about his patients and will do everything possible to meet or exceed your realistic expectations of care. This includes ensuring your comfort. If you would like to see if you are a candidate for PRO-NOX™ with your desired cosmetic procedure, contact our office today to schedule your consultation.

*Individual results may vary. Consult with Dr. Peña to see if you are a candidate.

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Specials and Events

HydraFacial Treatment Receive Free Jlo Glow add on Value of $50

Skinceuticals Special Buy 2 Skinceuticals Products and Get 3rd 50% OFF

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Before and After

Facelift Before and After Before and After Mommy Makeover Naples, FL Lip Augmentation Before and After Rhinoplasty Before and After ThermiTight Before and After Butt Lift Before and After
Individual results may vary. Click to View Results

Contact Us

Call 239-348-7362 Fax number: (239) 920-5205

Book a Plastic Surgery Appointment Get Directions

La Piel SPA Services & Injectables

Front of the La Piel Spa enterance

La Piel Spa – We also offer special services like facial chemical peels through La Piel Spa, our relaxing MediSpa. Our makeup specialists can work with you to show you the best makeup application techniques to enhance your appearance.

La Piel Full-Service Medical Spa Book at La Piel Spa
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Begin Your Aesthetic Journey

Whether you are exploring surgical options or scheduling aesthetic treatments, our team is here to guide you. We offer seamless online booking for consultations, injectable treatments, and aesthetic services.

Schedule Appointment - Peña Plastic SurgeryBook Treatments - La Piel Spa
Reception
6370 Pine Ridge Rd. Suite 101,
Naples, FL 34119
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Peña Plastic Surgery

The staff at the office of Naples Cosmetic Surgeon, Manuel Peña, MD, is truly what sets our Naples cosmetic surgery practice apart from other Florida providers. Our highly skilled professionals will go above and beyond to make your experience an exceptional one.

Location
6370 Pine Ridge Rd. Suite 101, Naples, FL 34119

Massage License no. MM#28349

Call Today
Office number: (239) 348-7362
Fax number: (239) 920-5205

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Our Success Stories

"Dr. Peña and his entire staff were so great. Dr. Peña took a lot of time with me to find out exactly what I wanted done and what my concerns were, he answered all my questions and was very thorough."

- Donna Fettig

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  • Before & After Results
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Apr 13

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Apr 6

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Thank you Greg from @napleslifestylemag for stopping by today 🤍
From mommy makeovers to “granny” makeovers, Dr. Peña is known for long-term, trusted results.

Whether it’s your first procedure or your last, Peña Plastic Surgery offers both surgical and med spa care—all in one place.

#naplesflorida #plasticsurgery #medspa #naplesbeauty
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Naples plastic surgeon, Dr. Manuel Peña’s website provides information on cosmetic surgery in the Naples, Fort Myers, Bonita Springs, & Estero, areas in Florida. This information is not to be taken as medical advice. Site powered by PUMC and AtlantisNet with copyrights reserved to dr-pena.com © 2026. This website does not contain medical advice and the use of this website does not create a physician/patient relationship between you and Dr. Manuel Peña. The photographs of models displayed on the headings and borders of this web site are for decorative purposes only. *Individual results may vary. Consult with Dr. Peña to see if you are a candidate. See before & after photos of Dr. Peña’s patients for possible results.