Hair thinning and hair loss is a common condition that is in part a result of the natural aging process. For many men and women, thinning hair and/or bald spots are a source of embarrassment. However, with advanced medical technology, you no longer need to be embarrassed by your bald spot and/or finding ways to cover up your head with caps, hats or wigs.
Dr. Manuel Peña is committed to using the latest non-surgical cosmetic technology to address face, body, and hair restoration concerns. He is experienced and specialized in performing a wide spectrum of innovative cosmetic procedures, including hair restoration treatments using microneedling techniques with platelet-rich plasma (PRP).
“Dr. Peña is always very professional, employing the latest technologies with a well-informed staff. Best of all, he has a warm demeanor and takes his time to explain and perform procedures.” - Ashley D. (Google Review)Read More Reviews
What is Microneedling with PRP?
Originally microneedling was performed with needles of varying lengths on a roller. These were replaced by battery-operated hand-held “microneedling” pens that were created based on tattoo machines. The purpose of the needle punctures was to stimulate wound healing, trigger collagen loss and production, and to enhance skin remodeling.
After the introduction of the “micro-pens,” topical agents were added to increase rejuvenation. Research showed that after having the treatment done, the procedure channels were open for a short time allowing delivery of products and substances to the deep (active) layers of the skin called the deep dermis. These areas happen to be where the hair follicles are. At first, only antioxidant vitamins such as topical Vitamin A and Vitamin C were used, then bleaching agents (Hydroquinones and Kojic Acid) were added to the list of treatment compounds.
With increasing clinical research in the field of regenerative medicine, researchers have found that the single most active post-procedure topical is autologous platelet-rich plasma (PRP). This utilizes a specific part of your own blood to “supercharge” the healing process. The platelets contain proteins (growth factors) that act as messengers to get the body to deliver “repair materials” to the area your treating. The combination of micro-needling plus PRP has been found effective in repairing sun damaged skin, acne scarring, surgical scars, burn scars, hyper, and hypopigmentation, as well as crinkly skin and fine lines.
Recently studies have also shown that this combination is particularly helpful with stimulating hair growth in certain types of thinning hair conditions. We are now combining this with a natural acellular matrix (ACELL) that when injected with the Platelet Rich Plasma it allows the PRP to stay where it was injected (near the hair follicles) so they can deliver the stimulating growth factors more effectively.
How is Microneedling with PRP Performed?
The procedure begins with a small amount of your blood that is drawn at Peña Plastic Surgery. The blood is then rapidly spun in a centrifuge to separate the PRP from the rest of your blood. To minimize discomfort, a topical anesthetic cream is administered to the area that will be treated. Some patients choose to have the area totally numbed with local anesthesia injections.
Rosa (our nurse who performs this procedure) then injects your plasma directly into your scalp with a specialized microneedling device to stimulate renewed blood supply and proper nutrients to your deprived hair follicles. The benefit of the microneedling technique allows for deeper penetration of PRP, amplifying the benefits of your hair restoration procedure.
Depending on the area treated, treatment can take 60 to 90 minutes. Several treatments may be needed for the best possible results, and treatments should be spaced 3 to 6 months apart.* Since PRP is derived from your own blood cells, there is limited risk for an allergic reaction or other adverse effects. Expect mild swelling and minimal soreness for a few days post procedure.
We also recommend the use of hair follicle supporting nutrients and vitamins which are included in the Nutrafol family of supplements (available at La Piel Spa).
Contact our office today to schedule your hair restoration consultation with board-certified plastic surgeon, Dr. Manuel Peña. We look forward to welcoming you here at Peña Plastic Surgery in Naples, FL.
Advanced Hair Growth Support from the Inside Out (Xtressé® and Nutrafol®)
Support Your Results with Physician-Recommended Hair Growth Solutions
Hair restoration is most effective when we address both the scalp and the body.
In addition to PRP, microneedling, and advanced in-office treatments, Peña Plastic Surgery offers physician-recommended internal hair growth support designed to improve follicle health, reduce shedding, and promote stronger, healthier hair growth from within.
Because every patient’s hair restoration journey is different, Dr. Peña and the La Piel MedSpa team offer personalized treatment plans using clinically backed nutraceutical support based on your specific concerns, lifestyle, and long-term goals.
Whether you are experiencing early thinning, age-related hair loss, hormonal shedding, stress-related shedding, or looking to enhance your PRP results, internal support can play a major role in long-term success.
Our Recommended Hair Growth Support Options (Xtressé® and Nutrafol®)
Xtressé® Hair Growth Gummies
Hair Restoration Support from the Inside Out
Xtressé® is a physician-exclusive, dermatologist-developed, biotin-free nutraceutical designed to support stronger, healthier hair growth using regenerative medicine principles.
Its proprietary X3-BioActive Blend™ helps reduce shedding, improve scalp health, and nourish hair follicles on a cellular level using clinically backed ingredients such as:
- NAD+
- Pumpkin Seed Extract
- Taurine
- Saw Palmetto
- Ashwagandha
- Pea Sprout Extract
Unlike many traditional supplements that rely heavily on high-dose biotin, Xtressé® is biotin-free, helping avoid interference with thyroid and cardiac lab testing.
Additional Benefits:
- Physician-exclusive formula
- Dermatologist-developed
- Clinically backed
- Biotin-free
- Sugar-free gummy delivery
- Easy daily compliance
- Anti-inflammatory and antioxidant support
Nutrafol® Women’s Hair Growth Pack
Clinically Proven Support for Women’s Hair Wellness
Nutrafol® is a physician-recommended hair growth nutraceutical specifically designed to target the root causes of female hair thinning.
This advanced system supports healthier hair growth by addressing:
- Hormonal changes
- Stress
- Aging
- Metabolism
- Lifestyle factors
- Nutritional deficiencies
Nutrafol® is especially effective for women experiencing menopausal thinning, postpartum changes, stress-related shedding, and long-term age-related hair loss.
Additional Benefits:
- Clinically proven formula
- Physician-recommended
- Comprehensive root-cause approach
- Long-term follicle support
- Designed specifically for women
- Excellent companion to PRP Hair Restoration
Combination Therapy for Optimal Results
For the most effective and lasting results, many patients benefit from combining:
Microneedling + PRP + Internal Hair Growth Support
This inside-out approach helps stimulate the scalp externally while strengthening follicle health internally—creating a stronger foundation for fuller, healthier hair growth.
Whether your plan includes Xtressé®, Nutrafol®, PRP, or a customized combination of treatments, our team will help determine the best strategy for your hair restoration journey.
Which Option Is Right for You?
Xtressé® vs Nutrafol®
Both options support healthier hair growth from within—but the best choice depends on your specific needs.
Xtressé® is ideal for:
- Men and women seeking daily hair wellness support
- Early hair thinning
- Increased shedding
- Stress or hormone-related hair changes
- Menopausal thinning
- PRP post-treatment support
- Patients seeking stronger, thicker-looking hair
Nutrafol® Women’s Pack is ideal for:
- Women 35+ experiencing thinning
- Hormonal hair loss
- Menopausal hair changes
- Stress-related shedding
- Postpartum thinning
- Long-term hair wellness support
Still have questions? Dr Pena and his team will help guide you toward the best option for your personalized treatment plan.


